Gangliogliomas: ubiquitous or not?
نویسنده
چکیده
In many publications, gangliogliomas are often referred to as “ubiquitous.” This term, meaning both “existing everywhere” or “constantly encountered,” is both correct and incorrect when referring to these tumors. Gangliogliomas may exist anywhere in the central nervous system, but are not commonly encountered. In this issue of the American Journal of Neuroradiology, two articles address the topic of gangliogliomas arising in the brain and spinal cord (1,2). The following are common issues raised regarding gangliogliomas.
منابع مشابه
Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH.
Gangliogliomas are generally benign neuroepithelial tumors composed of dysplastic neuronal and neoplastic glial elements. We screened 61 gangliogliomas [World Health Organization (WHO) grade I] for genomic alterations by chromosomal and array-based comparative genomic hybridization (CGH). Aberrations were detected in 66% of gangliogliomas (mean +/- SEM = 2.5 +/- 0.5 alterations/tumor). Frequent...
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Gangliogliomas represent the most frequent tumor entity in young patients suffering from chronic focal epilepsies. In a series of 326 gangliogliomas collected from the University of Bonn Epilepsy Surgery Program and other departments of neuropathology in Germany, Austria, and Switzerland, epidemiological findings and histopathological hallmarks of gangliogliomas are systematically reviewed. The...
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Gangliogliomas usually present as benign tumors corresponding to World Health Organization (WHO) Grade I. Very rarely, gangliogliomas show histological features of malignancy and are then classified as anaplastic gangliogliomas of WHO Grade III or IV. In most cases, anaplastic gangliogliomas developed after radiation therapy or progression from a pre-existing low-grade ganglioglioma. Here, we r...
متن کاملPosterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups
BACKGROUND Gangliogliomas are low-grade glioneuronal tumors of the central nervous system and the commonest cause of chronic intractable epilepsy. Most gangliogliomas (>70%) arise in the temporal lobe, and infratentorial tumors account for less than 10%. Posterior fossa gangliogliomas can have the features of a classic supratentorial tumor or a pilocytic astrocytoma with focal gangliocytic diff...
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ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 19 5 شماره
صفحات -
تاریخ انتشار 1998